The Wnt16 Monoclonal Antibody (CAB20899) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, developed for use in immunohistochemistry and immunofluorescence applications, is raised in rabbits and exhibits high reactivity with human samples.Wnt16 is a key player in the Wnt signaling pathway, which is essential for embryonic development, tissue homeostasis, and cell proliferation. Dysregulation of the Wnt pathway has been implicated in numerous diseases, including cancer, neurodegenerative disorders, and metabolic syndromes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Wnt16 Monoclonal Antibody
SKU:
CAB20899
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2862
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.
Purification Method
Affinity purification
Gene ID
51384
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Wnt16 Rabbit mAb (CAB20899) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
