Description
APMAP Antibody (PACO18574)
The APMAP Polyclonal Antibody (PAC018574) is a valuable tool for researchers studying APMAP, a protein involved in various biological processes, including lipid metabolism and cell proliferation. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the APMAP protein, this antibody allows for the detection and analysis of APMAP expression in different cell types, making it ideal for studies in metabolism, cell biology, and cancer research.
APMAP, also known as adipocyte plasma membrane-associated protein, plays a crucial role in lipid metabolism and has been implicated in the progression of certain types of cancer. Understanding the function and regulation of APMAP can provide insights into mechanisms of disease and potential therapeutic targets. This antibody offers researchers a reliable tool for investigating the role of APMAP in various physiological and pathological processes.
| Antibody Name: | APMAP Antibody (PACO18574) |
| Antibody SKU: | PACO18574 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human APMAP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18574(APMAP Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-7: Human placenta tissue, Human fetal liver tissue, PC3 cells, 231 cells, Hela cells, HepG2 cells, A549 cells, Primary antibody: PACO18574(APMAP Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18574(APMAP Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | C20orf3, also known as APMAP (adipocyte plasma membrane-associated protein), is a 416 amino acid, single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play a role in adipocyte differentiation. The gene encoding C20orf3 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception |
| Synonyms: | adipocyte plasma membrane associated protein |
| UniProt Protein Function: | APMAP: a single-pass type II membrane protein that may play a role in adipocyte differentiation. Belongs to the strictosidine synthase family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Enzyme, misc. Chromosomal Location of Human Ortholog: 20p11.2 Cellular Component: cell surface; membrane; integral to membrane Molecular Function:strictosidine synthase activity; arylesterase activity Biological Process: biosynthetic process |
| UniProt Code: | Q9HDC9 |
| NCBI GenInfo Identifier: | 24211474 |
| NCBI Gene ID: | 57136 |
| NCBI Accession: | Q9HDC9.2 |
| UniProt Secondary Accession: | Q9HDC9,Q6UVZ8, Q9GZS8, Q9NUB2, A8K514, B4DXG1, |
| UniProt Related Accession: | Q9HDC9 |
| Molecular Weight: | 32,161 Da |
| NCBI Full Name: | Adipocyte plasma membrane-associated protein |
| NCBI Synonym Full Names: | adipocyte plasma membrane associated protein |
| NCBI Official Symbol: | APMAPÂ Â |
| NCBI Official Synonym Symbols: | BSCv; C20orf3Â Â |
| NCBI Protein Information: | adipocyte plasma membrane-associated protein; protein BSCv |
| UniProt Protein Name: | Adipocyte plasma membrane-associated protein |
| UniProt Synonym Protein Names: | Protein BSCv |
| Protein Family: | Adipocyte plasma membrane-associated protein |
| UniProt Gene Name: | APMAPÂ Â |
| UniProt Entry Name: | APMAP_HUMAN |
