The AREG Antibody (CAB12680) is a high-quality antibody developed for reliable detection and analysis of target proteins. The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. RRID AB_2759526 Gene ID 374 Swiss Prot Synonym AR; SDGF; AREGB; CRDGF; AREG
This antibody is validated for use in IF/ICC, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
AREG Antibody
SKU:
CAB12680
Size:
100μL, 20μL
Reactivity:
Mouse
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
IF/ICCELISA
Recommended Dilution:
IF
/
ICC
1:50 - 1:200
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AR, SDGF, AREGB, CRDGF, AREG
Positive Sample:
-
Cellular Localization:
Membrane, Single-Pass Membrane Protein.
Calculated MW:
28kDa
Observed MW:
Refer to figures
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. RRID AB_2759526 Gene ID 374 Swiss Prot Synonym AR; SDGF; AREGB; CRDGF; AREG
Purification Method:
Affinity purification
Gene ID:
374
RRID:
AB_2759526
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Immunofluorescence analysis of NIH-3T3 cells using AREG Rabbit pAb (CAB12680) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
