The ARSK Antibody (PAC015560) is a high-quality polyclonal antibody designed for research involving ARSK, a protein involved in cellular processes. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunofluorescence. It binds specifically to the ARSK protein, allowing for accurate detection and analysis in different cell types, which makes it an excellent tool for studies in molecular biology and drug development.
ARSK is known for its role in cellular metabolism and has been linked to various diseases such as cancer and metabolic disorders. Understanding the functions and mechanisms of ARSK is essential for developing targeted therapies and diagnostic tools for these conditions. The ARSK Antibody is a valuable tool for researchers working in fields such as oncology, metabolic disorders, and drug discovery who are interested in studying the role of ARSK in health and disease.
Antibody Name:
ARSK Antibody (PACO15560)
Antibody SKU:
PACO15560
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human ARSK
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15560(ARSK Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15560(ARSK Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
Synonyms:
arylsulfatase family, member K
UniProt Protein Function:
ARSK: Belongs to the sulfatase familyProtein type: EC 3.1.6.-; Secreted, signal peptide; Secreted; HydrolaseChromosomal Location of Human Ortholog: 5q15Cellular Component: endoplasmic reticulum lumen; extracellular regionMolecular Function: arylsulfatase activity; metal ion bindingBiological Process: cellular protein metabolic process; sphingolipid metabolic process; glycosphingolipid metabolic process; post-translational protein modification
UniProt Protein Details:
NCBI Summary:
Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]
