The BAALC Antibody (CAB15513) is a high-quality antibody developed for reliable detection and analysis of target proteins. BAALC is a conserved mammalian protein expressed in neuroectodermal tissues and hematopoietic progenitor cells, first identified through gene expression studies in acute myeloid leukemia (AML) patients. Elevated BAALC expression in AML correlates with chemotherapy resistance and poor clinical outcomes, making it a clinically relevant prognostic marker.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
BAALC Antibody
SKU:
CAB15513
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BAALC
Positive Sample:
Mouse brain, Mouse skeletal muscle, Rat brain, Rat skeletal muscle
Cellular Localization:
Cytoplasm, Membrane.
Calculated MW:
16kDa
Observed MW:
19kDa
This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines.
Purification Method
Affinity purification
Gene ID
79870
RRID
AB_2762914
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BAALC Rabbit pAb (CAB15513) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
