The BCAS3 Polyclonal Antibody (CAB7274) is a valuable tool for researchers studying BCAS3, a protein involved in various cellular processes, including cell migration and invasion. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the BCAS3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for studies in cancer biology and metastasis research.BCAS3, also known as Breast Carcinoma Amplified Sequence 3, is associated with poor prognosis in various cancer types, including breast and ovarian cancer.
Its role in promoting tumor progression and metastasis makes it an attractive target for further investigation. By elucidating the functions of BCAS3, researchers can gain insights into the molecular mechanisms underlying cancer development and progression, potentially leading to the development of novel therapeutic strategies targeting BCAS3-mediated pathways.
Product Name:
BCAS3 Rabbit Polyclonal Antibody
SKU:
CAB7274
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_060149.3).
WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
MAAB; GAOB1; PHAF2; HEMARS; BCAS3
Positive Sample:
HeLa,BT474,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus, cytoskeleton.
Calculated MW:
101kDa
Observed MW:
115kDa
Enables several functions, including acetyltransferase activator activity; beta-tubulin binding activity; and histone acetyltransferase binding activity. Involved in cellular response to estrogen stimulus; positive regulation of catalytic activity; and positive regulation of transcription by RNA polymerase II. Located in nucleus; phagophore assembly site; and transcriptionally active chromatin. Biomarker of breast cancer.
Purification Method:
Affinity purification
Gene ID:
54828
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using BCAS3 Rabbit pAb (CAB7274) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
