The BIN3 Antibody (CAB15478) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blotting techniques. By targeting the BIN3 protein, this antibody allows for precise detection and analysis in a variety of cells, making it a valuable tool for studies in cell biology and cancer research.BIN3 is known to play a pivotal role in cellular functions, including cell cycle regulation and apoptosis. Its involvement in key processes makes it a promising target for investigations into cancer development and progression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
BIN3 Antibody
SKU:
CAB15478
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BIN3
Positive Sample:
A-549, A431, HeLa, Mouse kidney, Mouse spleen, Rat kidney
Cellular Localization:
Cytoplasm, Cytoskeleton.
Calculated MW:
30kDa
Observed MW:
35kDa
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
Purification Method
Affinity purification
Gene ID
55909
RRID
AB_2762876
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BIN3 Rabbit pAb (CAB15478) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
