The Biotinylated Anti-2B4 Antibody (HDLA032) is a valuable tool for researchers studying the 2B4 protein, a cell surface receptor involved in immune regulation and activation. This antibody, produced in-house at Assay Genie, is highly specific for detecting human samples and has been validated for use in various applications, including Western blotting and immunoprecipitation.2B4, also known as CD244, plays a crucial role in regulating immune responses and is particularly important in the function of natural killer (NK) cells and cytotoxic T lymphocytes. By targeting the 2B4 protein with this antibody, researchers can gain insights into the activation and inhibition mechanisms of these immune cells, making it a valuable tool for studies in immunology and cancer research.
The ability to detect and analyze 2B4 protein expression in different cell types provides researchers with a deeper understanding of immune system function and its implications for diseases such as cancer, viral infections, and autoimmune disorders. By utilizing the Biotinylated Anti-2B4 Antibody, researchers can advance their research efforts in unraveling the complexities of immune regulation and developing targeted therapies for various diseases.
SKU:
HDLA032
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM70
Synonyms:
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
