The Biotinylated Anti-Mesothelin Antibody (HDLA035) is a valuable tool for researchers studying mesothelin, a cell surface protein often overexpressed in various types of cancer, including mesothelioma and ovarian cancer. This antibody, produced in-house at Assay Genie, has been specifically biotinylated for easy detection and analysis in immunohistochemistry and other applications.Mesothelin is a promising target for cancer therapy due to its limited expression in normal tissues and high expression in cancer cells.
The Biotinylated Anti-Mesothelin Antibody (HDLA035) allows for precise detection of mesothelin in tumor samples, providing researchers with a powerful tool for understanding its role in cancer progression and developing targeted therapies.By utilizing this antibody, researchers can further explore the potential of mesothelin as a diagnostic marker and therapeutic target in various cancers, ultimately contributing to advancements in precision medicine and personalized treatment strategies.
Product Code:
HDLA035
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM73
Synonyms:
MSLN, Mesothelin, MPF
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
