The C6 Antibody (CAB10170) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly reactive with human samples and validated for Western blot applications. By binding to the C6 protein, it allows for detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.C6, also referred to as an immune inhibitory receptor, is crucial for maintaining immune homeostasis by regulating inflammation and suppressing allergic reactions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
C6 Antibody
SKU:
CAB10170
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
C6
Positive Sample:
Mouse liver, Mouse lung, Rat lung
Cellular Localization:
Secreted.
Calculated MW:
105kDa
Observed MW:
105-130kDa
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
Purification Method
Affinity purification
Gene ID
729
RRID
AB_2757697
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using C6 Rabbit pAb (CAB10170) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
