The CA10 Polyclonal Antibody (PAC014180) is a vital tool for researchers studying CA10, a gene involved in various cellular processes, including calcium signaling and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in immunohistochemistry applications. By targeting the CA10 protein, this antibody allows for precise detection and analysis in different cell types, making it ideal for investigations in the fields of molecular biology and cancer research.
CA10, also known as carbonic anhydrase X, plays a crucial role in maintaining pH balance within cells and is implicated in tumor progression and metastasis in certain cancers. Its significance in cellular function makes it a valuable target for research into cancer biology, as well as other fields such as metabolic disorders and neurodegenerative diseases. Understanding the role of CA10 is essential for developing targeted therapies that can effectively disrupt or enhance its function in disease processes.
Antibody Name:
CA10 Antibody (PACO14180)
Antibody SKU:
PACO14180
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human CA10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14180(CA10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.
Synonyms:
carbonic anhydrase X
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
