The Cadherin-6 Polyclonal Antibody (CAB8109) is a valuable tool for researchers studying Cadherin-6, a cell adhesion molecule involved in various biological processes, including cell-cell adhesion and tissue organization. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.Cadherin-6 is known to play a role in cell adhesion and migration, making it a key player in development, wound healing, and cancer metastasis. By binding specifically to Cadherin-6 protein, this antibody enables the detection and analysis of Cadherin-6 expression in different cell types, making it a versatile tool for studies in developmental biology, cancer research, and tissue engineering.
Understanding the function of Cadherin-6 is crucial for unraveling its contribution to various cellular processes and diseases. Research utilizing the Cadherin-6 Polyclonal Antibody paves the way for advancements in therapeutic strategies targeting Cadherin-6 in conditions such as cancer, developmental disorders, and regenerative medicine.
Product Name:
K-Cadherin (CDH6) Rabbit Polyclonal Antibody
SKU:
CAB8109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human K-Cadherin (K-Cadherin (CDH6)) (NP_004923.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
88kDa
Observed MW:
100kDa
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
Purification Method:
Affinity purification
Gene ID:
1004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using K-Cadherin (K-Cadherin (CDH6)) antibody (CAB8109) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
