The Casein Kinase 2 beta (CSNK2B) Monoclonal Antibody (CAB4519) is a high-quality antibody developed for reliable detection and analysis of target proteins. This high-quality antibody, derived from rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications.CK2β is a critical component of the CK2 holoenzyme, which plays a pivotal role in cell cycle regulation, DNA repair, apoptosis, and cellular signaling pathways. Dysregulation of CK2β has been linked to cancer, neurodegenerative diseases, and other disorders, making it a compelling target for drug development and therapeutic interventions.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Casein Kinase 2 beta (CSNK2B) Monoclonal Antibody
SKU:
CAB4519
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1069
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
1460
RRID
AB_2863285
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Casein Kinase 2 beta (CSNK2B) (CSNK2B) Rabbit mAb (CAB4519) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
Immunofluorescence analysis of NIH-3T3 cells using Casein Kinase 2 beta (CSNK2B) (CSNK2B) Rabbit mAb (CAB4519) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
