The CATSPER4 Polyclonal Antibody (PAC015939) is a valuable tool for researchers studying CATSPER4, a protein essential for sperm function and male fertility. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, enabling the detection and analysis of CATSPER4 in a variety of cell types.CATSPER4 is a key component of the CATSPER ion channel complex, which plays a critical role in sperm motility and fertilization.
Research on CATSPER4 is important for understanding male infertility and developing new treatments for reproductive disorders. By targeting CATSPER4, researchers can explore its function in sperm physiology and potentially discover novel strategies for enhancing fertility in men.Overall, the CATSPER4 Polyclonal Antibody is an essential tool for investigating the role of CATSPER4 in male reproductive biology and could lead to significant advances in the field of fertility research.
Antibody Name:
CATSPER4 Antibody (PACO15939)
Antibody SKU:
PACO15939
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human CATSPER4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO15939(CATSPER4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15939(CATSPER4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of thecation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
