The CBLC Antibody (CAB7789) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. RRID AB_2768732 Gene ID 23624 Swiss Prot Synonym CBL-3; RNF57; CBL-SL; CBLC
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
CBLC Antibody
SKU:
CAB7789
Size:
100μL, 20μL
Reactivity:
Human, Mouse
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CBL-3, RNF57, CBL-SL, CBLC
Positive Sample:
293T, Raji, U-937, Mouse kidney
Cellular Localization:
Plasma Membrane.
Calculated MW:
52kDa
Observed MW:
52kDa
This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. RRID AB_2768732 Gene ID 23624 Swiss Prot Synonym CBL-3; RNF57; CBL-SL; CBLC
Purification Method:
Affinity purification
Gene ID:
23624
RRID:
AB_2768732
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CBLC Rabbit pAb (CAB7789) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 90s.