The CBLN4 Polyclonal Antibody (PAC023410) is a valuable tool for researchers studying CBLN4, a member of the cerebellin protein family that plays a role in synaptic plasticity and neural development. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CBLN4 protein, researchers can detect and analyze its expression in various cell types, making it an essential tool for studies in neuroscience and neurodevelopmental disorders.CBLN4 is known for its involvement in modulating synaptic transmission and promoting the formation and function of neural circuits. Its expression in the brain suggests a crucial role in regulating neuronal communication and connectivity.
Research into CBLN4 may provide valuable insights into conditions such as autism, schizophrenia, and other neurological disorders characterized by disruptions in synaptic function and connectivity.By utilizing the CBLN4 Polyclonal Antibody, researchers can further explore the functions and mechanisms of CBLN4 in the brain, potentially leading to the development of novel therapeutic approaches for neurological conditions associated with synaptic dysfunction. Understanding the role of CBLN4 in synaptic plasticity and neural circuitry is essential for advancing our knowledge of brain function and identifying new targets for treating neurological disorders.
CBLN4: May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 20q13Cellular Component: extracellular space; synapse; cell junctionBiological Process: protein secretion
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012]
