The CCL17 Polyclonal Antibody (CAB2854) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and shows high reactivity with human samples, making it suitable for various research applications, including Western blotting.CCL17, also known as thymus and activation-regulated chemokine (TARC), plays a crucial role in recruiting immune cells to sites of inflammation and regulating immune responses. It is implicated in various diseases, including asthma, atopic dermatitis, and other allergic conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CCL17 Polyclonal Antibody
SKU:
CAB2854
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TARC, ABCD-2, SCYA17, A-152E5.3, CCL17
Positive Sample:
Recombinant Human CCL17/TARC Protein
Cellular Localization:
Secreted.
Calculated MW:
11kDa
Observed MW:
38-40kDa
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Purification Method
Affinity purification
Gene ID
6361
RRID
AB_2764679
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of Recombinant Human CCL17/TARC Protein (RP01374), using CCL17 Rabbit pAb (CAB2854) at 1:6000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 10ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
