The CD117/c-Kit Monoclonal Antibody (CAB23299) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced in mouse, is highly specific for human samples and has been validated for use in various applications, including Western blot, immunohistochemistry, and flow cytometry.CD117 (c-Kit) is a receptor tyrosine kinase that is essential for the development and function of a variety of cell types, including hematopoietic stem cells, mast cells, and melanocytes. Dysregulation of the CD117 signaling pathway has been implicated in various diseases, including cancer and certain hematologic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
CD117/c-Kit Monoclonal Antibody
SKU:
CAB23299
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC60558
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
16590
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from mouse lung, using CD117/c-Kit Rabbit mAb (CAB23299) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
