The CD2BP2 Antibody (CAB15777) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through rabbit immunization, has high specificity for human samples and has been validated for use in Western blotting applications.CD2BP2, also known as CD2 binding protein 2, is a crucial player in immune responses and has been implicated in various diseases, including cancer and autoimmune disorders. By binding to the CD2BP2 protein, this polyclonal antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights for studies in immunology and cancer research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CD2BP2 Antibody
SKU:
CAB15777
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LIN1, Snu40, FWP010, U5-52K, PPP1R59, CD2BP2
Positive Sample:
A-549, 293T, LO2
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
38kDa
Observed MW:
54kDa
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Purification Method
Affinity purification
Gene ID
10421
RRID
AB_2763196
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD2BP2 Rabbit pAb (CAB15777) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
