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Key Features

GenieFluor 488 Anti-Human CD68 Antibody [Y1/82A] (AGEL3313)

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SKU AGEL3313
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, k
Clone Y1/82A
Conjugation AF488
€112 - €450
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Description

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GenieFluor 488 Anti-Human CD68 Antibody [Y1/82A]

The GenieFluor 488 Anti-Human CD68 Antibody (Y1/82A) is a cutting-edge tool designed for precise detection of CD68, a key cell surface marker associated with macrophages and monocytes involved in immune responses and inflammation. This highly specific antibody, optimized for human samples, is ideal for a wide range of immunofluorescence applications, including immunohistochemistry and flow cytometry.CD68 is a crucial component of the innate immune system, playing a pivotal role in phagocytosis and antigen presentation. Its expression is commonly used to identify and characterize macrophages in various tissues and disease states. The GenieFluor 488 Anti-Human CD68 Antibody (Y1/82A) enables researchers to visualize and quantify CD68-positive cells with exceptional sensitivity and precision, facilitating detailed investigations into immune cell populations in both normal and pathological conditions.

With its high specificity and reliability, this antibody is a valuable tool for studies in immunology, inflammation, infectious diseases, and cancer research. By offering unparalleled insights into the dynamics of CD68-expressing cells, the GenieFluor 488 Anti-Human CD68 Antibody (Y1/82A) empowers scientists to deepen their understanding of immune responses and develop innovative therapeutic strategies targeted at modulating macrophage function in various disease contexts.

Product Title:GenieFluor 488 Anti-Human CD68 Antibody [Y1/82A]
SKU:AGEL3313
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Y1/82A
Synonyms:Macrosialin;
Host Species:Mouse
Reactivity:Human
Application:ICFCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor 488 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P34810
Gene ID:968 
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD68 is a 110 kD glycoprotein, also known as macrosialin, belonging to the sialomucin family. It is closely related to the family of acidic, highly glycosylated lysosomal-associated membrane proteins (LAMPs). CD68 is predominately expressed in cytoplasmic granules of monocytes/macrophages, dendritic cells, and granulocytes. It is one of the useful myeloid cell markers. Further studies have shown that CD68 is also expressed by a subset of hematopoietic progenitors, γ/δ T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells. The biological function of CD68 is still unknown.

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