The CDC42EP4 Polyclonal Antibody (PACO08321) is a critical tool for researchers studying CDC42EP4, a protein involved in regulating cell migration, adhesion, and cytoskeletal organization. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CDC42EP4, also known as CDC42 effector protein 4, is a key player in the CDC42 signaling pathway, which is essential for various cellular processes, including cell migration and invasion. By targeting CDC42EP4 with this antibody, researchers can accurately detect and analyze its expression levels in different cell types, providing valuable insights into its function in cellular physiology and its potential role in disease progression.
The CDC42EP4 Polyclonal Antibody is a valuable tool for investigations in cell biology, cancer research, and drug development, as understanding the mechanisms regulated by CDC42EP4 can lead to the development of targeted therapies for diseases such as cancer and metastasis. By using this antibody, researchers can further unravel the complex roles of CDC42EP4 in cellular processes and potentially identify novel therapeutic targets.
CDC42 effector protein (Rho GTPase binding) 4;CDC42EP4;BORG4;CEP4;KAIA1777;MGC17125;MGC3740 ;
UniProt Protein Function:
CDC42EP4: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts. Belongs to the BORG/CEP family.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 17q24-q25Cellular Component: microtubule cytoskeleton; cytoplasm; plasma membrane; endomembrane system; actin cytoskeletonMolecular Function: GTP-Rho bindingBiological Process: regulation of cell shape; positive regulation of pseudopodium formation; positive regulation of actin filament polymerization; Rho protein signal transduction
UniProt Protein Details:
NCBI Summary:
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]
