The CDH26 Polyclonal Antibody (PACO00498) is a valuable tool for research involving CDH26, a cell adhesion molecule that plays a crucial role in cell-cell interactions and tissue organization. This antibody, developed using rabbit immunization, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the CDH26 protein, researchers can effectively detect and analyze its expression in various cell types, making this antibody ideal for studies in developmental biology, cancer research, and tissue engineering.CDH26, also known as cadherin-26, is known for its involvement in cell adhesion processes, which are essential for maintaining tissue structure and function.
Its dysregulation has been linked to various diseases, including cancer and developmental abnormalities. By studying the role of CDH26 in cell adhesion and signaling pathways, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets for intervention.Overall, the CDH26 Polyclonal Antibody (PACO00498) is a valuable research tool that can help advance our understanding of cell adhesion mechanisms and their implications in disease. Its high specificity and sensitivity make it a reliable choice for researchers looking to explore the functions of CDH26 in various biological contexts.
Antibody Name:
CDH26 Antibody
Antibody SKU:
PACO00498
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human Cadherin-26.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CDH26; Cadherin-like protein 26; Cadherin-like protein VR20
UniProt Protein Function:
CDH26: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 20q13.33Cellular Component: integral to membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion
UniProt Protein Details:
NCBI Summary:
Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jul 2008]
