The CDKL2 Polyclonal Antibody (PAC021914) is a valuable tool for researchers studying CDKL2, a protein kinase involved in cell cycle regulation and cell proliferation. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CDKL2, also known as cyclin-dependent kinase-like 2, is a key player in controlling cell division and growth, making it a crucial target for cancer research and drug development. By binding to the CDKL2 protein, this antibody enables accurate detection and analysis of CDKL2 expression in various cell types, providing valuable insights into its role in tumorigenesis and potential therapeutic strategies.
Understanding the function and regulation of CDKL2 is essential for advancing our knowledge of cancer biology and identifying novel therapeutic targets for the treatment of various types of cancer. The CDKL2 Polyclonal Antibody is an essential tool for researchers aiming to unravel the complexities of cell cycle control and cell proliferation mechanisms.
Antibody Name:
CDKL2 Antibody (PACO21914)
Antibody SKU:
PACO21914
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human CDKL2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from 293 cells and Jurkat cells, using CDKL2 antibody.
CDKL2: a protein kinase of the CDKL family. Accumulates primarily in the cytoplasm, with a lower level in the nucleus.Protein type: Protein kinase, CMGC; Kinase, protein; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; CMGC group; CDKL familyChromosomal Location of Human Ortholog: 4q21.1Cellular Component: centrosome; nucleusMolecular Function: protein kinase activityBiological Process: sex differentiation; signal transduction
UniProt Protein Details:
NCBI Summary:
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]
