The CGB Antibody (PACO23669) is a high-quality polyclonal antibody designed for research involving CGB, a cell surface protein involved in various cellular processes. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in a variety of applications, including Western blotting.CGB, also known as chorionic gonadotropin beta, plays a crucial role in reproductive physiology and pregnancy. It is commonly used as a biomarker for pregnancy testing and monitoring. The CGB Antibody enables the detection and analysis of CGB protein in different cell types, making it an essential tool for research in reproductive biology and fertility studies.
The significance of CGB in reproductive health and pregnancy makes it a valuable target for investigating infertility, pregnancy complications, and hormonal regulation. By understanding the role of CGB, researchers can advance our knowledge of reproductive processes and potentially develop new diagnostic tools and therapeutic interventions in the field of reproductive medicine.
CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Secreted, signal peptide; Inhibitor; Secreted
Chromosomal Location of Human Ortholog: 19q13.32
NCBI Summary:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
