The CH25H Polyclonal Antibody (CAB24299) is a valuable tool for researchers studying CH25H, an enzyme involved in cholesterol metabolism and immune regulation. This antibody, produced in rabbits, shows high specificity for human samples and is recommended for use in Western blot applications. By binding to CH25H, this antibody allows for detection and analysis of the protein in various cell types, making it an essential reagent for studies in lipid metabolism, inflammation, and immune response regulation.CH25H, also known as cholesterol 25-hydroxylase, plays a crucial role in converting cholesterol into 25-hydroxycholesterol, which has been shown to exhibit antiviral and immune-modulatory properties.
Research on CH25H has implications for understanding the link between cholesterol metabolism and immune responses, as well as potential therapeutic interventions for infectious diseases and inflammatory conditions. The CH25H Polyclonal Antibody is a valuable tool for investigating the role of CH25H in these processes and advancing our knowledge of its function in health and disease.
Product Name:
Ch25h Polyclonal Antibody
SKU:
CAB24299
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 171-270 of human Ch25h (NP_003947.1).
Enables cholesterol 25-hydroxylase activity. Involved in B cell chemotaxis. Acts upstream of or within cholesterol metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; respiratory system; and skin. Orthologous to human CH25H (cholesterol 25-hydroxylase).
Purification Method:
Affinity purification
Gene ID:
9023
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using Ch25h Rabbit pAb (CAB24299) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
