Description
CLEC18A Antibody (PACO25793)
The CLEC18A Polyclonal Antibody (PAC025793) is a valuable tool for researchers studying CLEC18A, a type II transmembrane protein that plays a role in immune regulation and cell adhesion. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications. By binding specifically to the CLEC18A protein, this antibody enables the detection and analysis of CLEC18A expression in a variety of cell types, making it a versatile tool for immunology and cancer research studies.CLEC18A, also known as a C-type lectin domain family 18 member A, is involved in immune modulation and may have implications in diseases such as cancer, autoimmune disorders, and inflammatory conditions.
Understanding the function and expression of CLEC18A is crucial for advancing our knowledge of immune responses and developing targeted therapies for related pathologies. The CLEC18A Polyclonal Antibody provides researchers with a reliable means to investigate the role of CLEC18A in various biological processes, contributing to advancements in the field of immunology.
| Antibody Name: | CLEC18A Antibody (PACO25793) |
| Antibody SKU: | PACO25793 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human C-type lectin domain family 18 member A protein (27-446AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: CLEC18A antibody at 2µg/ml + Mouse stomach tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 50, 12 kDa Observed band size: 50 kDa . |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO25793 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human stomach tissue using PACO25793 at dilution of 1:100. |
| Synonyms: | C-type lectin domain family 18 member A (Mannose receptor-like protein 2), CLEC18A, MRLP2 |
| UniProt Protein Function: | CLEC18A: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: endoplasmic reticulum; endosome; extracellular space; Golgi apparatus Molecular Function:polysaccharide binding; protein binding |
| NCBI Summary: | This is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C-type lectin domains. These domains bind to carbohydrates in the presence of calcium, and may be involved in cell adhesion, immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012] |
| UniProt Code: | A5D8T8 |
| NCBI GenInfo Identifier: | 215274119 |
| NCBI Gene ID: | 348174 |
| NCBI Accession: | A5D8T8.3 |
| UniProt Secondary Accession: | A5D8T8,Q6DCB3, Q7Z5K9, Q96HH2, A8K1G9, |
| UniProt Related Accession: | A5D8T8 |
| Molecular Weight: | 11,762 Da |
| NCBI Full Name: | C-type lectin domain family 18 member A |
| NCBI Synonym Full Names: | C-type lectin domain family 18 member A |
| NCBI Official Symbol: | CLEC18AÂ Â |
| NCBI Official Synonym Symbols: | MRCL; MRCL1; MRLP2Â Â |
| NCBI Protein Information: | C-type lectin domain family 18 member A |
| UniProt Protein Name: | C-type lectin domain family 18 member A |
| UniProt Synonym Protein Names: | Mannose receptor-like protein 2 |
| Protein Family: | C-type lectin domain family |
| UniProt Gene Name: | CLEC18AÂ Â |
| UniProt Entry Name: | CL18A_HUMAN |
| Antibodies |
| CLEC18A Antibody (PACO08460) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
