The Clybl Polyclonal Antibody (PACO39630) is a valuable tool for researchers studying the role of Clybl in various cellular processes. Clybl, a protein involved in cellular metabolism and energy production, is essential for maintaining cellular function and homeostasis. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it reliable for use in Western blot applications. By targeting the Clybl protein, researchers can gain insight into its function and mechanisms of action in different cell types, providing valuable information for studies in metabolism, aging, and disease progression.
Given the importance of Clybl in cellular metabolism, this antibody is ideal for research in areas such as metabolic disorders, neurodegenerative diseases, and cancer. Understanding the role of Clybl in these contexts may lead to the development of novel therapeutic strategies targeting metabolic pathways and cellular energy regulation.
Western blot. All lanes: CLYBL antibody at 1µg/ml. Lane 1: Hela whole cell lysate. Lane 2: NIH/3T3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 34 kDa. Observed band size: 38 kDa.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39630 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO39630 at dilution of 1:100.
Background:
Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate.
CLYBL: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit-like subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Lyase; Mitochondrial; EC 4.1.-.-Chromosomal Location of Human Ortholog: 13q32Cellular Component: mitochondrionMolecular Function: metal ion binding; lyase activityBiological Process: metabolic process
