The CMTM1 Polyclonal Antibody (PACO22271) is a valuable tool for researchers studying CMTM1, a protein that plays a crucial role in regulating immune responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CMTM1 protein, this antibody allows for the detection and analysis of CMTM1 in various cell types, making it an ideal choice for studies in immunology and cancer research.CMTM1, also known as CKLF-like MARVEL transmembrane domain-containing protein 1, is involved in immune regulation and has been implicated in the development of various diseases, including cancer and autoimmune disorders.
Understanding the function of CMTM1 is essential for developing new therapies that target the immune system and for gaining insights into the underlying mechanisms of these diseases. With its high specificity and validated performance in Western blotting, the CMTM1 Polyclonal Antibody is a valuable tool for researchers looking to investigate the role of CMTM1 in immune responses and disease pathogenesis.
Antibody Name:
CMTM1 Antibody (PACO22271)
Antibody SKU:
PACO22271
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human CKLF1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunofluorescence analysis of MCF-7 cells, using CKLF1 antibody.
Background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).
Synonyms:
CKLF-like MARVEL transmembrane domain-containing protein 1; Chemokine-like factor superfamily member 1;
UniProt Protein Function:
CMTM1: a member of the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011]Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 16q21Cellular Component: extracellular space; integral to membraneMolecular Function: cytokine activityBiological Process: chemotaxis
