The CNNM4 Antibody (CAB17130) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blotting and immunohistochemistry applications.CNNM4 plays a crucial role in maintaining cellular magnesium levels, which are essential for various physiological processes such as DNA synthesis and energy metabolism. Dysregulation of CNNM4 has been linked to diseases like hypomagnesemia and epilepsy, making it a target of interest for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CNNM4 Antibody
SKU:
CAB17130
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ACDP4, CNNM4
Positive Sample:
NIH/3T3, Rat lung
Cellular Localization:
Basolateral Plasma Membrane, Plasma Membrane.
Calculated MW:
87kDa
Observed MW:
100kDa
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta.
Purification Method
Affinity purification
Gene ID
26504
RRID
AB_2768970
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using CNNM4 Rabbit pAb (CAB17130) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
