The COL23A1 Polyclonal Antibody (PACO8509) is a valuable tool for researchers studying COL23A1, a type VII collagen that plays a key role in skin elasticity and regeneration. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.COL23A1 is involved in maintaining the structure and function of the skin, and its dysregulation has been linked to various skin disorders and diseases.
By targeting COL23A1 with this polyclonal antibody, researchers can investigate its expression and function in different cell types, providing insights into its involvement in skin health and disease progression.Overall, the COL23A1 Polyclonal Antibody is a valuable tool for studying the role of COL23A1 in skin biology and pathology, offering new avenues for research in dermatology and regenerative medicine.
COL23A1: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 5q35.3Cellular Component: collagen; endoplasmic reticulum lumen; integral to membrane; plasma membraneBiological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis
UniProt Protein Details:
NCBI Summary:
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]
