The COL23A1 Polyclonal Antibody (PACO22038) is a valuable tool for researchers studying COL23A1, a type II transmembrane protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the COL23A1 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it ideal for investigations in the fields of cell biology and tissue engineering.
COL23A1, also known as collagen type XXIII alpha 1 chain, plays a crucial role in extracellular matrix organization and cell adhesion. Its involvement in these processes makes it a promising target for research on tissue development, wound healing, and cancer metastasis. Understanding the functions of COL23A1 is essential for advancing our knowledge of these biological pathways and potentially identifying novel therapeutic strategies for related diseases.
Antibody Name:
COL23A1 Antibody (PACO22038)
Antibody SKU:
PACO22038
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:100-1:500
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human Collagen XXIII alpha 1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunofluorescence analysis of HepG2 cells, using Collagen XXIII alpha 1 antibody.
Background:
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]
Synonyms:
Collagen alpha-1(XXIII) chain; COL23A1;
UniProt Protein Function:
COL23A1: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 5q35.3Cellular Component: collagen; endoplasmic reticulum lumen; integral to membrane; plasma membraneBiological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis
UniProt Protein Details:
NCBI Summary:
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]
