Description
COL9A1 Antibody (CAB6563)
The COL9A1 Antibody (CAB6563) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the COL9A1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for investigations in musculoskeletal biology and orthopedic research.COL9A1 is a crucial component of type IX collagen, which plays a key role in maintaining the structural integrity and mechanical properties of cartilage.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
| Product Name: | COL9A1 Antibody |
| SKU: | CAB6563 |
| Size: | 20μL, 100μL |
| Reactivity: | Rat |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | WASA AVKR RPRF PVNS NSNG GNEL CPKI RIGQ DDLP GFDL ISQF QVDK AASR RAIQ RVVG SATL QVAY KLGN NVDF RIPT RNLY PSGL PEEY SFLT TFRM TGST LKKN WNIW QIQD SSGK EQVG IKIN GQTQ SVVF SYKG LDGS LQTA AFSN LSSL FDSQ WHKI MIGV ERSS ATLF VDCN RIES LPIK PRGP IDID GFAV LGKL ADNP QVSV PFEL QWML IHCD PLRP RRET CHEL PARI TPSQ TTDE RGP | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | MED, EDM6, STL4, DJ149L1.1.2, COL9A1 |
| Positive Sample: | Rat lung, Rat kidney |
| Cellular Localization: | Secreted, Extracellular Matrix, Extracellular Space. |
| Calculated MW: | 92kDa |
| Observed MW: | 92kDa |
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
| Purification Method | Affinity purification |
| Gene ID | 1297 |
| RRID | AB_2767157 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using COL9A1 Rabbit pAb (CAB6563) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s. |
