The COX19 Polyclonal Antibody (PACO05677) is a valuable tool for researchers studying COX19, a protein involved in mitochondrial function and metabolism. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.COX19 plays a crucial role in cytochrome c oxidase (COX) biogenesis, an essential component of the electron transport chain in mitochondria. Dysregulation of COX19 has been implicated in various mitochondrial disorders, making it an important target for research into mitochondrial function and disease.
By binding to the COX19 protein, this antibody enables researchers to detect and analyze COX19 expression in different cell types, providing valuable insights into its role in mitochondrial metabolism and related diseases. With its high specificity and sensitivity, the COX19 Polyclonal Antibody is an essential tool for studies in molecular biology, biochemistry, and mitochondrial research.
Antibody Name:
COX19 Antibody (PACO05677)
Antibody SKU:
PACO05677
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:20000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the N-terminal region of human COX19.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
COX19; Cytochrome c oxidase assembly protein COX19; hCOX19
UniProt Protein Function:
COX19: May be required for the assembly of mitochondrial cytochrome c oxidase. Belongs to the COX19 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7p22.3Cellular Component: cytoplasm; mitochondrial intermembrane space; cytosolBiological Process: aerobic respiration; mitochondrial respiratory chain complex IV assembly
UniProt Protein Details:
NCBI Summary:
COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008]
