Description
COX7A2 Antibody (CAB8406)
The COX7A2 Antibody (CAB8406) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for Western blot applications. By binding specifically to the COX7A2 protein, this antibody enables the detection and analysis of this critical component in various cell types.COX7A2 is involved in the regulation of oxidative phosphorylation and energy metabolism within the cell. Dysfunction of COX7A2 has been linked to various diseases, including mitochondrial disorders and metabolic conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
| Product Name: | COX7A2 Antibody |
| SKU: | CAB8406 |
| Size: | 20μL, 100μL |
| Reactivity: | Human |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | MLRN LLAL RQIG QRTI STAS RRHF KNKV PEKQ KLFQ EDDE IPLY LKGG VADA LLYR ATMI LTVG GTAY AIYE LAVA SFPK KQE | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | VIIAL, COX7AL, COX7AL1, COXVIIAL, COXVIIa-L, COX7A2 |
| Positive Sample: | HeLa |
| Cellular Localization: | Mitochondrion Inner Membrane. |
| Calculated MW: | 9kDa |
| Observed MW: | 11kDa |
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
| Purification Method | Affinity purification |
| Gene ID | 1347 |
| RRID | AB_2769020 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of lysates from HeLa cells, using COX7A2 Rabbit pAb (CAB8406) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 10s. |
