The CPNE8 Polyclonal Antibody (PACO02488) is a valuable tool for researchers studying CPNE8, a protein involved in various cellular processes, including calcium signaling and membrane trafficking. This antibody, raised in rabbits, has high specificity and sensitivity for detecting CPNE8 in human samples, making it ideal for Western blot applications. By targeting the CPNE8 protein, researchers can explore its role in intracellular signaling pathways and its potential implications in diseases such as cancer and neurological disorders.CPNE8, also known as copine VIII, is a member of the copine family of proteins that are involved in mediating cellular responses to external stimuli.
Its role in calcium-dependent processes and membrane dynamics highlights its importance in cell biology and signaling. Research into CPNE8 can provide insights into its involvement in cell proliferation, differentiation, and migration, shedding light on potential therapeutic targets for various diseases.Overall, the CPNE8 Polyclonal Antibody (PACO02488) is a valuable tool for researchers interested in unraveling the functions of CPNE8 and its significance in cellular processes and disease pathology. Its high reactivity and specificity make it a reliable choice for studies in molecular biology, cell biology, and biomedical research.
Antibody Name:
CPNE8 Antibody
Antibody SKU:
PACO02488
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the N-terminal region of human Copine 8.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CPNE8; Copine-8; Copine VIII
UniProt Protein Function:
CPNE8: a member of the copine protein family with calcium-dependent phospholipid binding properties. Copines are ubiquitously expressed, phospholipid-binding proteins that have been conserved through evolution. Highest expression of CPNE8 mRNA is seen in the prostate, heart, and brain. Fusion to AML1 in a t(12;21) translocation causes aggressive acute myelogenous leukemia. Two alternatively spliced isoforms have been described.Protein type: Unknown functionChromosomal Location of Human Ortholog: 12q12
UniProt Protein Details:
NCBI Summary:
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
