The CRABP1 Monoclonal Antibody (CAB5434) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has been validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.CRABP1 is known to play a crucial role in cellular differentiation, proliferation, and apoptosis, making it a key player in developmental processes and cancer progression. By targeting CRABP1 with this antibody, researchers can gain valuable insights into the function and regulation of this protein in both normal and diseased states, paving the way for potential therapeutic interventions in cancer and other diseases affected by dysregulated retinoic acid signaling pathways.
This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CRABP1 Monoclonal Antibody
SKU:
CAB5434
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1991
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
RBP5, CRABP, CRABPI, CRABP-I, CRABP1
Positive Sample:
MCF7, NIH/3T3, Rat testis, Mouse testis
Cellular Localization:
Cytoplasm.
Calculated MW:
16kDa
Observed MW:
16kDa
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
Purification Method
Affinity purification
Gene ID
1381
RRID
AB_2863502
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CRABP1 Rabbit mAb (CAB5434) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Western blot analysis of lysates from Mouse testis, using CRABP1 Rabbit mAb (CAB5434) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
