The CRTC1 Antibody (CAB15412) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in Western blot applications.CRTC1 plays a crucial role in regulating gene expression in response to various cellular signals, making it a key player in pathways related to energy balance, stress response, and metabolic diseases. By targeting CRTC1 with this antibody, researchers can effectively detect and analyze the protein in a variety of cell types, providing insights into its functions and potential therapeutic implications.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
CRTC1 Antibody
SKU:
CAB15412
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MAML2, MECT1, Mam-2, TORC1, TORC-1, WAMTP1, CRTC1
Positive Sample:
Mouse brain
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
67kDa
Observed MW:
80kDa
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane.
Purification Method
Affinity purification
Gene ID
23373
RRID
AB_2762320
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using CRTC1 Rabbit pAb (CAB15412) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.