The CSDE1 Monoclonal Antibody (CAB21127) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using hybridoma technology, specifically targets the CSDE1 protein in various cell types and is suitable for use in applications such as immunofluorescence and immunohistochemistry.CSDE1, also known as cold shock domain-containing protein E1, is involved in mRNA stabilization, translation regulation, and maintenance of genomic integrity. Dysregulation of CSDE1 expression has been linked to various diseases, including cancer and neurodegenerative disorders, making it an important target for investigation in molecular and cellular biology research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
CSDE1 Monoclonal Antibody
SKU:
CAB21127
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC3050
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
UNR, D1S155E, CSDE1
Positive Sample:
HeLa, MCF7, Mouse skeletal muscle
Cellular Localization:
Cytoplasm.
Calculated MW:
89kDa
Observed MW:
89kDa
Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex.
Purification Method
Affinity purification
Gene ID
7812
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CSDE1 Rabbit mAb (CAB21127) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Western blot analysis of lysates from Mouse skeletal muscle, using CSDE1 Rabbit mAb (CAB21127) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.