Description
CSHL1 Antibody (PACO25989)
The CSHL1 Antibody (PAC025989) is a highly specific and sensitive tool for researchers studying CSHL1, a key protein involved in various cellular processes. This polyclonal antibody, produced in rabbits, has been validated for use in a variety of applications, including Western blot and immunohistochemistry.CSHL1, also known as Cold shock domain-containing protein C2, plays a crucial role in cell proliferation, differentiation, and apoptosis. It has been implicated in cancer development and progression, making it a compelling target for further investigation in oncology research.
The CSHL1 Antibody enables precise detection and analysis of CSHL1 protein expression in different cell types, providing valuable insights into its function and potential therapeutic implications.By using the CSHL1 Antibody, researchers can gain a deeper understanding of the role of CSHL1 in disease mechanisms and potentially identify novel strategies for targeted cancer therapy. Its high specificity and sensitivity make it a reliable tool for studying the complex functions of CSHL1 in a variety of research settings.
| Antibody Name: | CSHL1 Antibody (PACO25989) |
| Antibody SKU: | PACO25989 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Chorionic somatomammotropin hormone-like 1 protein (1-128AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: CSHL1 antibody at 2µg/ml + Human placenta tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 26, 23, 16, 15 kDa Observed band size: 26 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO25989 at dilution of 1:100. |
| Background: | May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation. |
| Synonyms: | Chorionic somatomammotropin hormone-like 1 (Chorionic somatomammotropin-like) (Lactogen-like), CSHL1, CSHP1 CSL |
| UniProt Protein Function: | CSHL1: May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation. Belongs to the somatotropin/prolactin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: extracellular region Molecular Function:hormone activity; metal ion binding |
| NCBI Summary: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14406 |
| NCBI GenInfo Identifier: | 313104096 |
| NCBI Gene ID: | 1444 |
| NCBI Accession: | Q14406.2 |
| UniProt Secondary Accession: | Q14406,Q0VDB2, D3DU26, D3DU27, |
| UniProt Related Accession: | Q14406 |
| Molecular Weight: | 222 |
| NCBI Full Name: | Chorionic somatomammotropin hormone-like 1 |
| NCBI Synonym Full Names: | chorionic somatomammotropin hormone-like 1 |
| NCBI Official Symbol: | CSHL1Â Â |
| NCBI Official Synonym Symbols: | CSL; CS-5; CSHP1; hCS-LÂ Â |
| NCBI Protein Information: | chorionic somatomammotropin hormone-like 1; growth hormone cluster; chorionic somatomammotropin CS-5 |
| UniProt Protein Name: | Chorionic somatomammotropin hormone-like 1 |
| UniProt Synonym Protein Names: | Lactogen-like |
| Protein Family: | Chorionic somatomammotropin hormone |
| UniProt Gene Name: | CSHL1Â Â |
| UniProt Entry Name: | CSHL_HUMAN |
| Antibodies |
| CSHL1 Antibody (PACO08629) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
