The CSTL1 Polyclonal Antibody (PAC013418) is a valuable tool for researchers studying CSTL1, a cysteine protease believed to play a role in immune regulation and inflammation. This antibody, generated in rabbits, shows strong reactivity with human samples and has been validated for use in Western blot applications. By binding to the CSTL1 protein, this antibody allows for the detection and analysis of CSTL1 in various cell types, making it an excellent choice for studies in immunology and inflammation-related research.CSTL1, also known as cathepsin L1, is a protease involved in various physiological processes, including immune cell functions and tissue remodeling.
Its role in immune regulation makes it a promising target for research into inflammatory diseases, autoimmune disorders, and cancer. Understanding the function of CSTL1 could lead to the development of novel therapies for these conditions by targeting this protease. Overall, the CSTL1 Polyclonal Antibody offers researchers a reliable tool for investigating the role of CSTL1 in immune regulation and inflammation, with potential implications for the development of new therapeutic approaches.
CSTL1: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 20p11.21Cellular Component: extracellular regionMolecular Function: cysteine protease inhibitor activity
UniProt Protein Details:
NCBI Summary:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]
