The CWC27 Antibody (PAC020411) is a highly specific and sensitive tool for detecting the CWC27 protein in research applications. This antibody has been rigorously tested and validated for use in Western blotting, immunofluorescence, and immunohistochemistry. With a high affinity for the CWC27 protein, this polyclonal antibody allows for accurate and reliable detection and analysis of CWC27 in various cell types and tissues.CWC27 is known to play a critical role in pre-mRNA splicing, making it a key player in gene expression regulation. Dysregulation of pre-mRNA splicing has been implicated in various diseases, including cancer and neurological disorders.
The CWC27 Antibody provides researchers with a valuable tool for studying the role of CWC27 in these diseases, as well as its potential as a therapeutic target.With its high specificity and sensitivity, the CWC27 Antibody is an essential tool for researchers studying gene expression regulation, pre-mRNA splicing, and the role of CWC27 in disease. Whether investigating basic biological processes or developing potential therapeutic interventions, this antibody is a valuable asset for advancing research in molecular biology and biomedicine.
Antibody Name:
CWC27 Antibody (PACO20411)
Antibody SKU:
PACO20411
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human CWC27
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20411(CWC27 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
CWC27 belongs to the cyclophilin-type PPIase family and contains 1 PPIase cyclophilin-type domain. There are two isoforms. PPIases accelerate the folding of proteins.
Synonyms:
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
UniProt Protein Function:
SDCCAG10: PPIases accelerate the folding of proteins. Belongs to the cyclophilin-type PPIase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 5.2.1.8; RNA splicing; Spliceosome; IsomeraseChromosomal Location of Human Ortholog: 5q12.3Molecular Function: peptidyl-prolyl cis-trans isomerase activityBiological Process: nuclear mRNA splicing, via spliceosome
