Description
CYP2A13 Antibody (PACO64658)
The CYP2A13 Polyclonal Antibody (PAC064658) is a crucial tool for researchers studying the cytochrome P450 family member CYP2A13. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the CYP2A13 protein, this antibody allows for the detection and analysis of CYP2A13 in various cell types, making it essential for research in pharmacology and toxicology.CYP2A13 is a key enzyme involved in the metabolism of several harmful compounds found in tobacco smoke, making it a target of interest in studies related to smoking-related diseases such as lung cancer and cardiovascular disorders.
By understanding the function and regulation of CYP2A13, researchers can gain valuable insights into the mechanisms of toxicity and potential therapeutic interventions in these disease contexts. The CYP2A13 Polyclonal Antibody provides a valuable tool for investigating the role of CYP2A13 in drug metabolism and disease susceptibility.
| Product Name: | CYP2A13 Antibody |
| Product Code: | PACO64658 |
| Size: | 50µL |
| Target Names: | CYP2A13 |
| Species Reactivity: | Human |
| Host Species: | Rabbit |
| Antigen Species: | Human |
| Tested Applications: | ELISA, IF; Recommended dilution: IF:1:100-1:500 |
| Isotype: | IgG |
| Clone ID: | N/A |
| Conjugate: | Non-conjugated |
| Clonality: | Polyclonal |
| Antigen: | Recombinant Human Cytochrome P450 2A13 protein (252-354aa) |
| Form: | Liquid |
| Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Aliases: | Cytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13), CYP2A13 |
| Uniprot ID: | Q16696 |
| Background: | Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. |
| Research Area: | Cardiovascular |
