Description
CYP2S1 Antibody (PACO08717)
The CYP2S1 Polyclonal Antibody (PACO08717) is a powerful tool for researchers studying the cytochrome P450 2S1 enzyme, which plays a key role in the metabolism of various compounds in the body. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CYP2S1 enzyme, researchers can accurately detect and analyze its expression in a variety of cell types, making it an essential tool for studies in drug metabolism, toxicology, and cancer research.
The CYP2S1 enzyme is involved in the metabolism of endogenous and exogenous compounds, including drugs, carcinogens, and environmental toxins. Understanding the function and regulation of CYP2S1 is crucial for elucidating its role in drug metabolism and metabolic activation of procarcinogens. Research into the activity of CYP2S1 may lead to the development of novel therapeutic strategies for cancer treatment and drug development.
| Antibody Name: | CYP2S1 Antibody (PACO08717) |
| Antibody SKU: | PACO08717 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human CYP2S1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | cytochrome P450, family 2, subfamily S, polypeptide 1; |
| UniProt Protein Function: | CYP2S1: Has a potential importance for extrahepatic xenobiotic metabolism. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase Chromosomal Location of Human Ortholog: 19q13.1 Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm Molecular Function:iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; epoxygenase P450 pathway |
| NCBI Summary: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96SQ9 |
| NCBI GenInfo Identifier: | 48428134 |
| NCBI Gene ID: | 29785 |
| NCBI Accession: | Q96SQ9.2 |
| UniProt Secondary Accession: | Q96SQ9,Q9BZ66, |
| UniProt Related Accession: | Q96SQ9 |
| Molecular Weight: | 504 |
| NCBI Full Name: | Cytochrome P450 2S1 |
| NCBI Synonym Full Names: | cytochrome P450, family 2, subfamily S, polypeptide 1 |
| NCBI Official Symbol: | CYP2S1Â Â |
| NCBI Official Synonym Symbols: | CYPIIS1Â Â |
| NCBI Protein Information: | cytochrome P450 2S1; cytochrome P540, subfamily IIS, polypeptide 1 |
| UniProt Protein Name: | Cytochrome P450 2S1 |
| UniProt Synonym Protein Names: | CYPIIS1 |
| Protein Family: | Cytochrome |
| UniProt Gene Name: | CYP2S1Â Â |
| UniProt Entry Name: | CP2S1_HUMAN |
