The DCBLD2 Polyclonal Antibody (PACO08755) is a valuable tool for researchers studying DCBLD2, a transmembrane protein involved in cell adhesion and migration processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.DCBLD2, also known as discoidin, CUB and LCCL domain-containing protein 2, plays a crucial role in angiogenesis and tumor progression, making it a potential target for cancer research. By targeting DCBLD2, researchers can gain valuable insights into the mechanisms underlying cancer development and progression, ultimately leading to the development of targeted therapies.
With its ability to specifically bind to DCBLD2, this antibody enables the detection and analysis of DCBLD2 expression in various cell types, furthering our understanding of its role in disease pathology. By utilizing this antibody in their studies, researchers can uncover new insights into the function of DCBLD2 and its potential as a therapeutic target in cancer treatment.
discoidin, CUB and LCCL domain containing 2;DCBLD2;CLCP1;ESDN ;
UniProt Protein Function:
DCBLD2: a type-I transmembrane protein. May be involved in vascular remodeling and influence vascular smooth muscle cell proliferation. Contains a CUB domain and a coagulation factor V/VIII homology domain, similar to the structure of the neuropilins. Plays a role in cell motility. SEMA4B appears to be one of its ligands. Strongly expressed in nerve bundles. Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells. Increased in lung cancers during the process of tumor progression. A target of EGF signaling in the A431 cervical cancer cell-line. Two isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesion; Membrane protein, integralChromosomal Location of Human Ortholog: 3q12.1|3Cellular Component: cell surface; integral to plasma membraneMolecular Function: protein bindingBiological Process: negative regulation of cell growth; wound healing
