The Ddit4l Polyclonal Antibody (PAC048058) is a valuable tool for researchers studying the role of Ddit4l in cellular processes and disease. Ddit4l, also known as DNA damage-inducible transcript 4-like protein, is involved in cellular response to stress, particularly in regulating cell growth and survival pathways.This antibody, generated in rabbits, is highly specific to human samples and is optimized for use in Western blot applications. By targeting the Ddit4l protein, researchers can explore its function in various cellular contexts, including cancer research and studies on cellular stress responses.
Ddit4l is a promising target for investigation due to its potential involvement in diseases such as cancer, neurodegenerative disorders, and metabolic diseases. Understanding the role of Ddit4l in cellular pathways could lead to the development of novel therapeutic strategies aimed at modulating its activity for clinical benefit.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO48058 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO48058 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Synonyms:
DNA damage-inducible transcript 4-like protein (HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2), DDIT4L, REDD2 RTP801L
UniProt Protein Function:
DDIT4L: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Belongs to the DDIT4 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 4q24Cellular Component: cytoplasmMolecular Function: protein binding
