The Dectin-1/CLEC7A/CD369 Polyclonal Antibody (CAB23668) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It allows for the detection and analysis of the Dectin-1 protein in various cell types, making it an essential tool for studies in immunology and cancer research.Dectin-1, a C-type lectin receptor, plays a key role in recognizing and responding to fungal pathogens, making it a critical component of the immune system. Its function in innate immunity and inflammatory responses has made it a target for research into infectious diseases, autoimmune disorders, and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
Dectin-1/CLEC7A/CD369 Polyclonal Antibody
SKU:
CAB23668
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
Email for sequence
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
BGR, beta-GR, Clecsf12, Dectin-1/CLEC7A/CD369
Positive Sample:
Mouse lung
Calculated MW:
27kDa
Observed MW:
27kDa
Predicted to enable (1->3)-beta-D-glucan binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including phagocytosis, recognition; positive regulation of cytokine production involved in inflammatory response; and response to fungus. Predicted to be active in cell surface. Is expressed in brain; gut; limb; musculature; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A).
Purification Method
Affinity purification
Gene ID
56644
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse lung, using Dectin-1/CLEC7A/CD369 Rabbit pAb (CAB23668) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
