The DHRS2 Antibody (CAB6446) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications including Western blot and immunohistochemistry.DHRS2, also known as dehydrogenase/reductase 2, plays a crucial role in maintaining cellular homeostasis by regulating retinol levels and lipid metabolism. Dysregulation of DHRS2 has been linked to various diseases including metabolic disorders, neurological conditions, and cancer.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
DHRS2 Antibody
SKU:
CAB6446
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HEP27, SDR25C1, DHRS2
Positive Sample:
Mouse testis, Mouse skeletal muscle, Rat testis
Cellular Localization:
Mitochondrion Matrix, Nucleus.
Calculated MW:
30kDa
Observed MW:
27kDa
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members of this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative promoter use and alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
10202
RRID
AB_2767048
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using DHRS2 Rabbit pAb (CAB6446) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Immunofluorescence analysis of HeLa cells using DHRS2 Rabbit pAb (CAB6446). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
