The DHX32 Polyclonal Antibody (PACO08832) is a valuable tool for researchers studying DHX32, a protein involved in RNA metabolism and cellular stress response. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blotting.DHX32, also known as RNA helicase DHX32, plays a crucial role in RNA processing and is implicated in various cellular processes, including RNA splicing and translation. Its involvement in cellular stress response suggests its potential role in diseases related to stress, such as cancer and neurodegenerative disorders.
By targeting DHX32 with this antibody, researchers can detect and study the protein in different cell types, providing insights into its function and potential therapeutic targets.Overall, the DHX32 Polyclonal Antibody is a valuable tool for researchers interested in the role of DHX32 in RNA metabolism and cellular stress response, offering opportunities for further exploration in the fields of molecular biology and disease research.
DHX32: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008]Protein type: Helicase; EC 3.6.4.13Chromosomal Location of Human Ortholog: 10q26.2Cellular Component: cytoplasm; spliceosomeMolecular Function: ATP-dependent RNA helicase activity; protein bindingBiological Process: nuclear mRNA splicing, via spliceosome
UniProt Protein Details:
NCBI Summary:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008]
