The DIRAS1 Polyclonal Antibody (PACO00707) is a valuable tool for researchers studying DIRAS1, a small GTPase protein that plays a crucial role in various cellular processes, including cell growth, survival, and migration. This antibody, produced in rabbits, is highly specific for DIRAS1 in human samples and has been validated for use in Western blot applications.DIRAS1, a member of the Ras superfamily, has been implicated in cancer progression and metastasis, making it a promising target for cancer research.
By binding to DIRAS1, this antibody enables researchers to detect and analyze the protein in different cell types, providing insights into its functions and potential therapeutic implications.The DIRAS1 Polyclonal Antibody is a valuable tool for scientists studying signal transduction pathways, tumor biology, and cell migration. Its high specificity and sensitivity make it an ideal choice for investigating the role of DIRAS1 in various diseases and biological processes.
Antibody Name:
DIRAS1 Antibody
Antibody SKU:
PACO00707
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Di-Ras1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
DIRAS1; GBTS1; RIG; GTP-binding protein Di-Ras1; Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1
UniProt Protein Function:
DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: GTP binding; GTPase activity; mitogen-activated protein kinase bindingBiological Process: positive regulation of MAP kinase activity
UniProt Protein Details:
NCBI Summary:
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004]
