The ECHS1 Polyclonal Antibody (CAB3845) is a valuable tool for researchers studying ECHS1, a key enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ECHS1 protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for investigations in metabolic disorders and cancer research.ECHS1, or enoyl-CoA hydratase, plays a crucial role in breaking down fatty acids for energy production within the mitochondria. Dysregulation of ECHS1 has been implicated in various metabolic diseases, highlighting its importance as a therapeutic target.
By studying ECHS1 activity, researchers can gain valuable insights into metabolic dysfunction and potential treatment strategies for metabolic disorders and cancer.Overall, the ECHS1 Polyclonal Antibody is a reliable tool for researchers seeking to explore the role of ECHS1 in metabolic pathways and its potential implications in disease. Its specificity and sensitivity make it a valuable asset for studies aiming to unravel the complexities of fatty acid metabolism and its impact on cellular function.
Product Name:
ECHS1 Rabbit Polyclonal Antibody
SKU:
CAB3845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-290 of human ECHS1 (NP_004083.3).
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
Purification Method:
Affinity purification
Gene ID:
1892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ECHS1 Rabbit pAb (CAB3845) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 30s.
